Figure 1

Figure1Questions

• Quick Quiz

What most likely accounts for this patient’s nail discoloration and distal onycholysis?

A 57-year-old cis woman presents with progressive nail changes. The fingernails have yellow-brown discoloration and distal onycholysis. The patient has metastatic breast cancer and is on chemotherapy.

What is the mechanism of action of the chemotherapeutic agent that most likely accounts for her nail findings?
Select an option to see full answer details. Image credit: @nguyendermatology

• Epidermal growth factor inhibitor

• Microtubule depolymerization inhibitor

• RNA synthesis inhibitor

• Proteasome inhibitor