Skin discoloration in a 84-year old female. CBC shows low pl | Figure 1
Skin discoloration in an 84-year-old female
CBC shows low platelet count (2 G/l).
What is this presentation? What should be included in the differential diagnosis?
Similar cases
Patient: 28-year-old female, married, nulligravida
Setting: Preconception counseling visit
Referral Reason: History of TTP in her last pregnancy 9 months ago with family history of thrombotic thrombocytopenic purpura (TTP) in multiple siblings; seeking risk assessment and pregnancy planning guidance.
Given the strong family history, female clustering, and pregnancy-specific onset, there is a high clinical suspicion of congenital TTP (Upshaw-Schulman syndrome), an autosomal recessive deficiency of ADAMTS13.
She was sent for ADAMTS 13 it was borderline 52% (reference > 61)
Positive pathogenic variant gene.
Platelet count, RFT, LDH, Peripheral blood smear were all normal.
Question: Does she need FFP prior to conception?
Description: This 80-year-old patient came to the hospital vomiting blood and has this discoloration on her legs.
Blood tests show that she has anemia.
No diagnosis was able to be made till now.
Description: Platelets of 16.
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Description: A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back. She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets. Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.
Description: A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days. Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.
Description: Patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this EKG that would warrant further work-up or is this just a pediatric EKG?