Here is a leukemia case for blood cancer month #blood15. Thi | Figure 1

%27%3e%3cg%20id=%27Group-14%27%20transform=%27translate(13.000000,%20103.176124)%27%3e%3cg%20id=%27Group-Copy-5%27%20transform=%27translate(0.000000,%20182.676124)%27%3e%3crect%20id=%27Rectangle-8%27%20fill=%27%23E2E0DE%27%20x=%270%27%20y=%270%27%20width=%2736%27%20height=%2736%27%20rx=%2718%27%3e%3c/rect%3e%3cpath%20d=%27M28,27.6503435%20C28,22.127496%2023.5228474,17.6503435%2018,17.6503435%20C12.4771525,17.6503435%208,22.127496%208,27.6503435%20M18,16.3472505%20C20.8165136,16.3472505%2023.099749,14.0640151%2023.099749,11.2475015%20C23.099749,8.43098783%2020.8165136,6.1477524%2018,6.1477524%20C15.1834863,6.1477524%2012.9002509,8.43098783%2012.9002509,11.2475015%20C12.9002509,14.0640151%2015.1834863,16.3472505%2018,16.3472505%20Z%27%20id=%27Combined-Shape%27%20fill=%27%23FFFFFF%27%20fill-rule=%27nonzero%27%3e%3c/path%3e%3c/g%3e%3c/g%3e%3c/g%3e%3c/g%3e%3c/svg%3e)

Deleted account

Some actions are only available when you log in.

Here is a leukemia case for blood cancer month #blood15. This is a monocytic leukemia in a peds patient. Wbc was >500k initially, platelets were <10k, hgb was 3. Patient was too unstable for a BM and LP but signs indicate CNS involvement. Don't mind the grey boxes. #Figure1 put it in because it has facial recognition software built in.

Why you should join Figure 1

Case Descriptions

  1. Patient Details: A 27-year-old female, G2P1001, who is in the second trimester of her current pregnancy, presents to the emergency department with complaints of fever, fatigue, and chin numbness which has been present for the last week without any changes. On examination, the numbness in the chin is confirmed. Additionally, she is found to have hepatosplenomegaly. Laboratory testing is ordered, and before results are obtained, the laboratory reports the presence of blasts in the peripheral smear. Oncology is consulted, and flow cytometry indicates precursor B-cell Acute Lymphoblastic Leukemia (Pre-B-ALL), based on the strong expression of CD19, CD22, CD79a, TdT, HLA-DR, and cytoplasmic IgM, and negativity for CD20 in a population of cells consistent with blasts. A rush cytogenetics workup is positive for t(9;22) (Ph). Systemic therapy is to be initiated.

  2. Case Summary: This is a mature B cell leukemia. Morphologically, neoplastic cells have too much cytoplasm to be blasts. Flow cytometry shows the abnormal population is 72% of WBCs and expresses CD5, CD19, CD20, and surface kappa light chain, indicating it's a B cell leukemia/lymphoma with differentials including mantle-cell-lymphoma and transformed chronic-lymphocytic-leukemia, as well as leukemic diffuse-large-B-cell-lymphoma. Mantle-cell-lymphoma was ruled out by cytogenetics for t(11;14).

  3. Acute Leukemia Consideration: A case of acute leukemia is presented without specific details.

  4. Bone Infarction After Treatment: Imaging demonstrates bone infarction after autologous bone marrow in patients with acute lymphocytic leukemia.

  5. Chest Pain Case Study: A 52-year-old man presented with chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis. He has a history of hypertension and smoking. On examination, bibasilar crackles were noted.

  6. Pruritus Case: An engaged 28-year-old woman presented with intense pruritus over the lower back, revealing multiple small vesicles predominantly in the lumbar region.

  7. Infant Case: A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days, revealing multiple small pustules with inflammatory signs.

  8. Teen Case: A teen presented after a collapse without previous chest pain or cardiac history, raising questions on EKG features.

Conclusion

Each of these cases provides critical insights and learning opportunities for medical professionals, showcasing a variety of symptoms and disease presentations.