monarchE Shows Survival Benefit With Adjuvant Abemaciclib Ac | Figure 1

monarchE Shows Survival Benefit With Adjuvant Abemaciclib Across All Nodal Burdens
Post in Breast Pathology, Endocrinology, Research, Breast Cancer, Hematology, Oncology

Updated results from the monarchE trial presented at SABCS 2025 showed that the addition of adjuvant abemaciclib to endocrine therapy was associated with meaningful reductions in recurrence risk and improvements in survival among patients with HR-positive, HER2-negative, node-positive early breast cancer. With extended follow-up, benefits in overall survival, invasive disease-free survival, and distant recurrence-free survival were observed across N1, N2, and N3 disease. Treatment effects appeared consistent regardless of nodal burden, offering further context for risk stratification and long-term adjuvant treatment decision-making.

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