In India, 80% of acute liver failure is viral (mostly HBV or | Figure 1
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Case Overview
In India, 80% of acute liver failure is viral (mostly HBV or HEV) while in the west, only 20% are viral. In image 1, the diseased liver is exposed. In image 2, the healthy liver has been prepared. In image 3, the donor liver is re-perfused. Here at Apollo Chennai, over 400 liver transplants have been performed. #apollohospitals
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Hepatocellular Carcinoma (HCC)
Hepatocellular carcinoma (HCC) is a primary liver malignancy known to occur majorly in patients with liver cirrhosis or those with a harbinger of risk factors like viral hepatitis, autoimmune liver disease, alpha-1 antitrypsin deficiency, alcoholic liver disease, and nonalcoholic fatty liver disease. The incidence of HCC has risen in the past 2 decades and currently ranks as the sixth most common cause of cancer-related death worldwide. Most cases are seen in adulthood, and only a very small percentage have been reported in adolescents with risk factors. The 2 pathologic subtypes of pediatric HCC are classic and fibrolamellar. Here, we discussed a very interesting rare case of a healthy male teenager with no apparent liver disease or risk factor who presented with right-upper-quadrant pain, normal alpha-fetoprotein level, and abdominal ultrasound showing a large hepatic mass. A liver biopsy was positive for HCC with fluorescent in situ hybridization showing a PRKACA complex gene pattern, favoring the fibrolamellar type.
Classic example of #Cirrhosis in an explanted liver from a ~70 year-old woman who received a liver transplant for #Nonalcoholic-steatohepatitis (NASH).
This post is submitted in two parts to show the histology of the liver pancreas and bone marrow of a recent post from a male in sixties with end stage liver and pancreas disease. Images part 1 liver and pancreas (five images).
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