%27%3e%3cg%20id=%27Group-14%27%20transform=%27translate(13.000000,%20103.176124)%27%3e%3cg%20id=%27Group-Copy-5%27%20transform=%27translate(0.000000,%20182.676124)%27%3e%3crect%20id=%27Rectangle-8%27%20fill=%27%23E2E0DE%27%20x=%270%27%20y=%270%27%20width=%2736%27%20height=%2736%27%20rx=%2718%27%3e%3c/rect%3e%3cpath%20d=%27M28,27.6503435%20C28,22.127496%2023.5228474,17.6503435%2018,17.6503435%20C12.4771525,17.6503435%208,22.127496%208,27.6503435%20M18,16.3472505%20C20.8165136,16.3472505%2023.099749,14.0640151%2023.099749,11.2475015%20C23.099749,8.43098783%2020.8165136,6.1477524%2018,6.1477524%20C15.1834863,6.1477524%2012.9002509,8.43098783%2012.9002509,11.2475015%20C12.9002509,14.0640151%2015.1834863,16.3472505%2018,16.3472505%20Z%27%20id=%27Combined-Shape%27%20fill=%27%23FFFFFF%27%20fill-rule=%27nonzero%27%3e%3c/path%3e%3c/g%3e%3c/g%3e%3c/g%3e%3c/g%3e%3c/svg%3e)

# Hydroxyurea (hydroxycarbamide) for sickle cell disease - Cochrane Review

There is evidence to suggest that hydroxyurea may be effective in decreasing the frequency of pain episodes and other acute complications in adults and children with sickle cell anaemia of HbSS or HbSβºthal genotypes and in preventing life‐threatening neurological events in those with sickle cell anaemia at risk of primary stroke by maintaining transcranial Doppler velocities.

[Read more](https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD002202.pub3/full)

---

### Diagnosis added by author

Diagnosis: sickle cell

---

### More about this case

Resolved

### Why you should join Figure 1

- Share your knowledge with our global community of healthcare professionals
- Get help from experts in your field
- Learn from our library of real-world cases and quizzes

---

#### Similar cases

\
\
[Sickle blood cells (left) normal blood cells (right)](/content/case-detail/145c0337-f25f-46a1-9b8e-5a71c523c8c0/index.html)

\
\
[Clubbing in a 29yo M with sickle cell anemia](/content/case-detail/2cf77edc-80d1-4119-ac5c-e77c1a0f0244/index.html)

\
\
[Bony infarcts in a 21 yo male with sickle cells anaemia.](/content/case-detail/31a062a4-1c5b-4432-b4d4-4c64d45ab5bf/index.html)

\
\
[Peripheral blood smear, 26M, AA, came in for assault. No PMH with hospital...](/content/case-detail/479fb219-5896-4287-8140-fbc1317fd1c6/index.html)

\
\
[A 52-year-old man presented with a 20-minute history...](/content/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a/index.html)

\
\
[A 28-year-old woman presented with a 3-day history...](/content/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5/index.html)

\
\
[A 4-month-old male infant presented with skin lesions...](/content/case-detail/48f41642-b9db-4089-b120-a94ee52328de/index.html)

\
\
[Patient in late teens presenting after a collapse...](/content/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5/index.html)