A 32-year-old man with primary marrow failure is being prepa | Figure 1
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A 32-year-old man with primary marrow failure is being prepared for bone marrow transplant. The operation is successful, but 2 to 3 days after the procedure, the patient complains of severe diarrhea, which contains a significant amount of blood and mucus. The attending intern notices some yellowing of the skin and orders liver function tests. Serum bilirubin is elevated, and all the liver enzymes are above the normal levels. The patient also develops erythematous macules that are beginning to turn necrotic. What is the most likely reason for this patient’s current medical condition?
A. Acute graft-versus-host disease (GVHD)
B. Chronic GVHD
C. Hyperacute marrow rejection
D. Acute transplant rejection
E. Chronic graft rejection
Question from Immunology for Medical Students, 3rd Edition. ISBN: 9780702068010. Copyright © 2017 by Elsevier, Inc.
pt had skin cancer removed from lower leg and skin graft (from thigh) to wound. Staples removed 5 days ago. I had this photo sent via text with patient wondering what he should put on wound (he did not feel as though anything was wrong with graft).
What do people think? Graft rejection? Does wound need debriding?
Skin GVHD in a patient day +16 after allogeneic matched unrelated transplant.
GVHD vs SJS in a bone marrow transplant patient. Receiving steroids, photopheresis.
In India, 80% of acute liver failure is viral (mostly HBV or HEV) while in the west, only 20% are viral. In image 1, the diseased liver is exposed. In image 2, the healthy liver has been prepared. In image 3, the donor liver is re-perfused. Here at Apollo Chennai, over 400 liver transplants have been performed. #apollohospitals
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