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#papillary-urothelial #Carcinoma #TCC of the #ureter

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Based on this histologic appearance, what is the dx?](https://app.figure1.com/case-detail/44fef774-9948-40ad-90aa-709159eb8fbe)

Here is a case of of an invasive squamous cell carcinoma of the larynx, specifically the right aryepiglottic fold.
I’ve marked some helpful anatomical landmarks on the first picture to help orient yourself — we are viewing the larynx from the posterior aspect (as if the patient were facing away from us). You can see the yellow tumor at the right AE fold which extends inferior and medial, across the midline. The black suture on the right was marked by the surgeon as the closest mucosal margin at the right AE fold.
In the 2nd pic, I show a cross section of the tumor (present at the top middle part of the picture) in relationship to maybe important structures/spaces. Evaluation of the cricoid cartilage, thyroid cartilage, pre-epiglottic space, and the hyoid bone (among several others!) are crucial in determining stage.
With just a handful of the needed anatomical terms and locations mentioned in this case, you can see how these cases can be quite challenging from both an anatomic pathology and a surgical point of view.](https://app.figure1.com/case-detail/67018829-2908-4491-af21-303cc02abc44)

PLEASE refer to previous posts as i summarize this rare cancer (3%) of all lung cancer - Large Cell neuroendocrine carcinoma ( with extremely poor prognosis ( four additional histology images are presented. IT is all but a death sentence as we must find ways of bringing large clinical studies from all around the world to combat this deadly form of lung cancer ( notice the relatively young age of patient with this devastating disease initially detected at STAGE IV)](https://app.figure1.com/case-detail/71bd3154-20de-4280-9065-c20ed20679ba)

Squamous cell carcinoma](https://app.figure1.com/case-detail/7f25b1db-e0f6-483a-9d5f-4436a135f488)

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A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis.
He had a history of hypertension, long-term smoking, and a sedentary lifestyle.
On physical examination, bibasilar crackles were noted on lung auscultation. An electrocardiogram (ECG) was performed in the primary care setting, and the patient was promptly referred to the emergency department.](https://app.figure1.com/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a)

A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back. She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets.
Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.](https://app.figure1.com/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5)

A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days. Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.](https://app.figure1.com/case-detail/48f41642-b9db-4089-b120-a94ee52328de)

patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)