Path-case4: A common central nervous system neoplasm… | Figure 1

azor

Medical Student

Path-case4: A common central nervous system neoplasm…

45 years-old male with recent neurological symptoms, MR imaging showed a large heterogenous mass in the left frontal lobe, a CT-guided needle biopsy was performed.

Histological H&E examination of the biopsy shows a proliferation of highly atypical and pleomorphic cells with high nucleocytoplasmic ratio, a microvascular proliferation with endothelial hyperplasia was noted (Red arrows), several necrosis regions were seen with a pseudo-palisading pattern ( Black arrows).

These findings are compatible with a Glioblastoma (Grade IV Astrocytoma).

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