intact #Eyeball removed for choroidal #Melanoma. While small | Figure 1

JLpath

Pathologists' Assistant

intact #Eyeball removed for choroidal #Melanoma. While smaller choroidal melanomas can be treated with radiation, once the size expands to almost the entire eye, removal is usually necessary. Like any malignant tumor, this can also metastasize to distant organs. While still quite a rare tumor, choroidal melanoma is the most common primary malignant eye tumor. Within the choroid (underneath the retina), there are melanocytes (pigmented cells), which is how melanoma can develop in a location not typically associated with melanoma.

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Intraocular mass centered on posterior choroid. Histology shows mitotically active lesion with mixed epithelial and spindle cell morphology. Note the prominent macronucleoli. Focal areas of pigment formation were seen. MelA stain is positive, confirmatory of #uveal-melanoma

63 male relatively healthy for age. No vision loss noticed per pt. OD is clear and healthy. 11x10 mm solid pigmented choroidal lesion. 4 mm raised. Bscan shows low to mod internal reflectivity. Negative fluid/heme/orange pigment. Large nevus vs small melanoma. Thoughts? Patient sent for melanoma eval, as we do not treat them.

update from previous post. OCT and B-scan of choroidal #Melanoma. Oct shows overlying fluid and bscan shows 3.3mm thickness.

choroidal melanoma. Orange arrow is mushroom shaped lesion, blue is cornea

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