Cardiovascular Disease Risk in Patients with Rheumatic Disea | Figure 1
Cardiovascular Disease Risk in Patients with Rheumatic Diseases
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Key Points:
- Adults with rheumatoid arthritis (RA) have an ∼1.5 times higher risk of cardiovascular disease (CVD) even with no traditional CVD risk factors, and incidence rates increase substantially with number of CVD risk factors.
- Low-density lipoprotein (LDL) or high-density lipoprotein (HDL) particles or apolipoproteins (apoB or apoA1) may be more reliable CVD risk factors than cholesterol (total, LDL-cholesterol, or HDL-cholesterol) concentrations because of chronic inflammation.
- In RA, current CVD risk factors likely underestimate the extent of subclinical atherosclerosis.
- Inflammation may directly cause myocardial injury and heart failure.
- Disease activity is a strong risk factor for CVD and mortality and a key target for CVD risk reduction.
Key Points from Clinics in Geriatric Medicine (Volume 33, Issue 1, February 2017, Pages 105-117) © 2016 Elsevier Inc.
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