CincyKidsRad

Cincinnati Children's Radiology

Coronal image from an F18-FDG PET in a patient with Langerhans cell histiocytosis (LCH) shows uptake within the collapsed vertebral body (arrow). LCH is the most common cause of vertebra plana in a child.

LCH is an oncologic disorder causing abnormal proliferation of histiocytes. In children, other causes of vertebra plana include leukemia, osteomyelitis, osteoporosis (usually related to medications such as long-term steroid therapy), and metastatic disease.

FridayQuizDay #Quiz #FridayQuiz

Why you should join Figure 1

• Share your knowledge with our global community of healthcare professionals
• Get help from experts in your field
• Learn from our library of real-world cases and quizzes

Similar cases

Typical case of...? Hint: long bones, vertebrae, ribs with same appearance.](https://app.figure1.com/case-detail/27d581e9-20db-49b5-af3f-4a8f96c0dbb7)

Sagittal (image 1) and axial (image 2) CT of the thoracic spine show an abnormal appearance of the occiput, thoracic vertebral bodies, and visible ribs. The skull base is thickened and sclerotic with a ground-glass matrix. Vertebral bodies are enlarged with a ground-glass matrix. Pathologic fractures with vertebral plana are present at multiple levels. The findings are typical of polyostotic fibrous dysplasia. Other entities that can cause multiple lucent lesions in the skull include metastatic neuroblastoma or Langerhans' cell histiocytosis. Lesions that can cause expansion of the skull include metastatic neuroblastoma, beta thalassemia, and sickle cell disease.](https://app.figure1.com/case-detail/3c87af55-c523-4e59-8dfb-cb932d225efd)

Sagittal T1 image in a 3 year old girl with central diabetes insipidus shows a thickened pituitary infundibulum (red arrow) and absent T1 bright posterior pituitary (blue arrow). In children, Langerhans cell histiocytosis (LCH), as in this case, and germinoma are the primary considerations. The infundibulum is the most frequent location for intracranial LCH involvement. #NeuroWednesday](https://app.figure1.com/case-detail/4b435df2-2efd-476b-95f2-a0177ca0c2e3)

Collapse of C7 vertebra with prevertebral tissue swelling, 5 yr old with neck pain 2 weeks. ? Osteo, eosinophilic granuloma, AVN? No other history available.](https://app.figure1.com/case-detail/8ee51235-3635-4edb-9935-80555db8687d)

A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis. He had a history of hypertension, long-term smoking, and a sedentary lifestyle. On physical examination, bibasilar crackles were noted on lung auscultation. An electrocardiogram (ECG) was performed in the primary care setting, and the patient was promptly referred to the emergency department.](https://app.figure1.com/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a)

A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back. She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets. Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.](https://app.figure1.com/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5)

A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days. Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.](https://app.figure1.com/case-detail/48f41642-b9db-4089-b120-a94ee52328de)

patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)