Whole body PET/CT with F-18-iPSMA. This tracer allow us to d | Figure 1

dvd_crdz

Nuclear Medicine

Whole body PET/CT with F-18-iPSMA.

This tracer allows us to detect metastases in prostate cancer. iPSMA is a molecule targeting prostate-specific membrane antigen, a transmembrane protein overexpressed in prostate cancer and all the metastatic lesions. Here we can see an example of node metastases and visceral metastases to the liver. With molecular imaging techniques, we are now able to detect metastases even with PSA as low as 0.4ng/ml in some series.

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#nuclearmedicine #molecularimaging #SPECT/CT #prostatecancer #urology #oncology #radiology #unclearmedicine #radiotherapy #prostatespecificmembraneantigen #99mTc #bonescan #boneimaging #radioactive #radiotracers
SPECT/CT 99mTc-EDDA/HYNIC-iPSMA (PSMA IMAGING) and 99mTc-HMDP (BONE IMAGING).
64 years old male patient with very high risk prostate cancer (NCCN, risk stratification) sent to our service for initial stratification. We performed the requested bone imaging study. As part of our protocol we are complementing the studies with specific prostate cancer radiotracer, as we can see. There is a clear correlation between metastasic bone lesions in both studies, but with PSMA imaging we can actually spot the primary tumor (yellow arrow) and additional pelvic nodes (second image).



This is a bone scan of an 86-year-old man, who was diagnosed with prostate cancer. The goal of the study was to exclude bony metastases.
What phenomenon can we see here and how can it be explained?](https://app.figure1.com/case-detail/06edff0a-9746-4ddb-ab32-a263f630f6bf)



Here is his bone scan. Most of the darker areas represent metastatic lesions from prostate cancer.](https://app.figure1.com/case-detail/243417aa-d940-4a67-946f-3f3b4b628a25)



M 75YO #Prostate-specific-antigen-(PSA) 1636.2ng/ml prostate cancer](https://app.figure1.com/case-detail/306cbc1f-b1af-434c-acad-8f4047de9e50)



patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)