Melanoma, an aggressive skin cancer resulting from the malig | Figure 1

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Melanoma, an aggressive skin cancer resulting from the malignant transformation of melanocytes, was once considered uncommon. Now, the annual incidence is rising faster than any other malignancy, more than doubling in the U.S in the past 30 years. Australia and New Zealand claim the world’s highest incidence of melanoma, though the extensive skin cancer screening program in Australia has helped to decrease the average tumor depth at the time of diagnosis. This patient presented with anemia secondary to bleeding from these cutaneous melanomatous metastases. Image credit: @a_sh

Small intestine metastatic lesion from malignant melanoma](https://app.figure1.com/case-detail/154a9541-88e9-4a63-bfb5-dfbf2a7ead00)

Malignant melanoma](https://app.figure1.com/case-detail/70a39da5-2b38-4df4-befb-7b63cc736996)

“ Melanoma “ is a type of skin cancer. It develops from skin cells called melanocytes. There are other types of skin cancer. In this Melanoma it’s 4th stage and there’s metastasis to the lung and bone](https://app.figure1.com/case-detail/75d73fe9-d422-4a29-82d8-c3111fcc616e)

A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis. He had a history of hypertension, long-term smoking, and a sedentary lifestyle. On physical examination, bibasilar crackles were noted on lung auscultation. An electrocardiogram (ECG) was performed in the primary care setting, and the patient was promptly referred to the emergency department.](https://app.figure1.com/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a)

A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back. She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets. Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.](https://app.figure1.com/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5)

A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days. Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.](https://app.figure1.com/case-detail/48f41642-b9db-4089-b120-a94ee52328de)

patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)

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