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### part II — 63 yo with headache (refer to recent post)

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!["In this analysis of 222 offspring of mothers infected with SARS-CoV-2, compared with the offspring of 7550 mothers in the control group (not infected) delivered during the same period, we observed neurodevelopmental diagnoses to be significantly more common among exposed offspring, particularly those exposed to third-trimester maternal infection," they write.  The study included 7772 mostly singleton live births across six hospitals in Massachusetts between March and September 2020, including 222 (2.9%) births to mothers with SARS-CoV-2 infection confirmed by polymerase chain reaction testing during pregnancy.  In all, 14 of 222 children born to SARS-CoV-2-infected mothers (6.3%) were diagnosed with a neurodevelopmental disorder in the first year of life vs 227 of 7550 unexposed offspring (3%) (unadjusted odds ratio [OR], 2.17; 95% CI, 1.24 - 3.79; P = .006).  In models adjusted for preterm delivery, as well as race, ethnicity, insurance status, child sex and maternal age, COVID-exposed offspring were significantly more likely to receive a neurodevelopmental diagnosis in the first year of life (adjusted OR, 1.86; 95% CI, 1.03 - 3.36; P = .04).  The magnitude of the association with neurodevelopmental disorders was greater with third-trimester SARS-CoV-2 infection (adjusted OR, 2.34; 95% CI, 1.23 - 4.44; P = .01).  The majority of these diagnoses reflected developmental disorders of motor function or speech and language.  The researchers note the finding of an association between prenatal SARS-CoV-2 exposure and neurodevelopmental diagnoses at 12 months are in line with a "large body of literature" linking maternal viral infection and maternal immune activation with offspring neurodevelopmental disorders later in life.  They caution, however, that whether a definitive connection exists between prenatal SARS-CoV-2 exposure and adverse neurodevelopment in offspring is not yet known, in part because children born to women infected in the first wave of the pandemic haven't reached their second birthday — a time when neurodevelopment disorders such as autism are typically diagnosed.  There is also the risk for ascertainment bias arising from greater concern for offspring of infected mothers who were ill during pregnancy. These parents may be more inclined to seek evaluation, and clinicians may be more inclined to diagnose or refer for evaluation.  Source: JAMA Network Open.](https://app.figure1.com/case-detail/21208f3a-c39f-4406-a4fd-e0415d975fe3)

### About 7 days after cardiac arrest from drug overdose.
Cerebral perfusion scan showed no flow to the brain.

### Middle Aged Gentleman POD #1 CABG x3. 
Out of Bed with Physical Therapy doing amazing, willing and able disputed being with PA Cath, Pacer, Arterial Line, Chest tubes, Cordis and the list continues in CCU. This is what makes my day. Early Mobility and Therapy in the ICU's is a must. Please don't under estimate your rehab team.

### A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis.
He had a history of hypertension, long-term smoking, and a sedentary lifestyle. On physical examination, bibasilar crackles were noted on lung auscultation. An electrocardiogram (ECG) was performed in the primary care setting, and the patient was promptly referred to the emergency department.

### A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back.
She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets. Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.

### A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days.
Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.

### Patient in late teens presenting after a collapse,
No chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?
