MutterMuseum

Sometimes visitors to our museum are disappointed that not everything is "real" - we make no apologies for our collection of medical models! Models were very useful for teaching doctors how to diagnose pathology and disease, because they lasted longer than cadavers, and were sometimes easier to procure.

This model demonstrates smallpox pimples on a wax arm. Smallpox caused hundreds of millions of deaths in the 20th century alone, and was eradicated in 1979 through vaccination. The smallpox vaccine was the first successful vaccine.

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Review question(s)
How effective or harmful are different HPV vaccine schedules (i.e. number and timing of doses) and different HPV vaccines in females and males?
Main results
These results are based on research evidence to 27 September 2018. We analysed 20 studies involving 31,940 people. Studies comparing two doses of HPV vaccine to three doses, or comparing the time interval between doses, focus on immune system responses rather than infection or disease outcomes. Conclusion
A two‐dose schedule of HPV vaccines in young females results in immune system responses that are comparable with a three‐dose schedule. In males, the quadrivalent HPV vaccine appears to be effective in the prevention of external genital lesions and genital warts. Quadrivalent and nonavalent HPV vaccines in young women result in similar levels of protection against cervical, vaginal, and vulval precancer lesions and cancer.