Giant platelet to the right. #Neutrophils for size compariso | Figure 1

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Giant platelet to the right. #Neutrophils for size comparison


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Cochrane Review

Cochrane Review; one study was eligible for inclusion in the review. This study was stopped after recruiting only nine participants because it had taken three years to recruit the nine participants (the study had planned to recruit 60 participants in two years). No ongoing studies were found.

Background: In people with bone marrow disorders bleeding can be a problem due to a low platelet count, or because the platelets do not work properly, or both. Platelet transfusions can be given when bleeding occurs in order to stop the bleeding, or before bleeding occurs in order to prevent it.

It is currently unclear if the best transfusion policy is to give platelet transfusions only when bleeding occurs or to give them to prevent bleeding.

Conclusion: No evidence is available to help decide whether giving platelet transfusions to treat bleeding is as good as giving platelet transfusions when the platelet count is below a prespecified level. There is an urgent need for good-quality studies to answer the questions of this review.

cbc results, 7 yo WM, one day hx of low grade #Fever sore throat, RST negative

Here in the hematology lab, a donated unit of whole blood is separated into its components by centrifugation and apheresis techniques. Image 3 demonstrates (from R to L) platelets, still mixed with some RBCs and Buffy coat, fresh plasma, packed RBCs, and a unit of fresh platelets. All blood products are irradiated and leukocyte-depleted before use.

A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis.

A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back.

A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days.

patient in late teens presenting after a collapse, no chest pain, no previous cardiac history.