Pregnant Hcv patient | Figure 1

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Pregnant HCV patient

25 yrs old female patient, pregnant in three months, on routine examination during pregnancy, she discovered that she is a hepatitis C virus patient and PCR is +ve for HCV. She asked what is the effect of this infection on her fetus during pregnancy, labor, and lactation, and what is her management during pregnancy?


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Sorry if the image isn't rotated. Hepatitis C. Is it common at your place? Took hold of this report today of a female patient 30 years old whose complaint was fever on/off with pain abdomen. This report is 3 months old. She has improved on conservative treatment. I want to know how to approach a Hepatitis C patient?

Cochrane Review; 6 studies. Is the antimalarial drug mefloquine efficacious & safe for preventing malaria in pregnant women living in stable transmission areas?
• Compared with sulfadoxine-pyrimethamine, mefloquine chemoprevention in HIV-uninfected women: reduces risks of maternal peripheral parasitaemia (presence of malaria parasites in the blood of women) & anemia at delivery; makes no difference in the prevalence of adverse maternal outcomes (e.g. low birth weight, prematurity, stillbirths & abortions, & congenital malformations) & in the incidence of clinical malaria episodes during pregnancy; increases risks of drug-related adverse events including vomiting, fatigue/weakness, & dizziness.
• Compared with cotrimoxale prophylaxis alone, mefloquine chemoprevention plus cotrimoxazole in HIV-infected women: reduces risks of maternal peripheral parasitaemia at delivery & the risk of placental malaria; makes no difference in the prevalence of adverse pregnancy outcomes & in the incidence of clinical malaria episodes during pregnancy; increases risks of drug-related adverse events e.g. vomiting & dizziness.
Key messages: Mefloquine is efficacious and safe in terms of adverse pregnancy outcomes (e.g. low birth weight, prematurity, stillbirths & abortions, & congenital malformations) but is worse tolerated than other antimalarial drugs.

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