Aspergillus flavus (green arrow), A. fumigatus (blue arrow) | Figure 1
pier_brollo
Family Medicine
Aspergillus flavus (green arrow), A. fumigatus (blue arrow) and Candida albicans (yellow arrow) isolated from the same BAL sample in a 12 yo male with cystic fibrosis.
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A typical picture of aspergilloma (invasive pulmonary infection by the fungus species Aspergillus). Round mass is in the cavity inside the lung with an air layer and resemble a meniscus or whisk - called "halo sign".
Aspergillus?](https://app.figure1.com/case-detail/4b7816f5-cccc-4341-a250-76481344ba53)
Photos from fungal culture of a bronchial washing. What two fungi do you see?](https://app.figure1.com/case-detail/61e1f50c-5cdc-487a-aca9-66bc5f6e0b52)
Frontal chest radiograph (image 1) in a child with acute lymphoblastic leukemia status post bone marrow transplant shows a cystic lesion (arrow) in the left mid lung. A solid component is present along the inferior aspect of the lesion with a surrounding crescent of air. Axial (image 2) and coronal (image 3) CT demonstrate a thick-walled cystic mass (arrow) with an internal component showing central cavitation. Scattered areas of ground-glass opacity are present in both lungs.
Teaching point: In immunocompromised children, pulmonary aspergillosis commonly manifests as nodules or masses with cavitation. The air crescent sign reflects separation of necrotic lung tissue from the cavity wall and is most often seen during immune recovery rather than early infection. Associated ground-glass opacities may represent hemorrhage or inflammatory change, and imaging findings should be interpreted in conjunction with clinical status and microbiologic data.