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Erythroderma with #Lymphedema

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Are anticholinergic drugs or withdrawal of anticholinergic drugs effective in the treatment of tardive dyskinesia in people with schizophrenia or other similar mental health problems?

Cochrane Review; 2 studies (30 people).
Background.
The main treatment of these symptoms are antipsychotic drugs. However, these drugs can have debilitating side-effects. Tardive dyskinesia is an involuntary movement that causes the face, mouth, tongue and jaw to convulse, spasm and grimace. It is caused by long-term use, or high doses, of antipsychotic drugs, is difficult to treat and can be incurable. Many people being treated with antipsychotic medication also receive anticholinergic drugs to try to reduce some of these movement side-effects. There is, however, evidence from animal experiments that anticholinergic drugs could cause tardive dyskinesia.
Key results.
There were sparse findings from two small and poorly reported trials. It is uncertain whether giving anticholinergic drugs is helpful in the treatment of tardive dyskinesia for people who are taking antipsychotic medication. It is also uncertain whether the withdrawal of anticholinergic medication improves the symptoms of tardive dyskinesia.
Quality of the evidence.
Available evidence is very low or low quality, limited, and small scale. More high quality research data is needed.

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