A diet rich in fibers and applied to mice by the researcher | Figure 1

PedroPharmacist

Pharmacist

A diet rich in fibers and applied to mice by the researcher Angélica Thomaz Vieira (UFMG), reduced in animals the inflammatory response induced by Crystals of uric acid, which shows benefits for the treatment of gouty arthritis and relief of its symptoms such as intense pain, swelling and redness in the joints.

With the diet, the mice had a better response to inflammation. The animals were fed for 14 days with enriched diet of a type of soluble fiber (Pectin), found in citrus peel and some vegetables. In animals that consumed fibers, there was a reduction in clinical signs and inflammation compared to other mice.

According to Angélica, the treatments resulted in the resolution of the inflammatory response, preventing tissue damage and dysfunction - alteration in the tissue that prevents it from performing its functions and that may lead to the development of other diseases - improving clinical signs such as ache.

The research also evaluated the importance of substances that result from metabolites and cause reduction in the disease.

They can reach the bloodstream and cause the death of neutrophils, directly related to inflammation in gout.

Source: Journal of Leukocyte Biology.

Similar cases

Results of experiments performed with mice suggest that inhibiting the action of the protein known as cheerin may present as an efficient strategy to prevent bone loss linked to inflammatory diseases. Burner is a molecule produced mainly by adipocytes, but is also expressed in several organs. There is evidence that this protein is increased in the bloodstream of people obese or suffering from type 2 diabetes, dyslipidemia, osteoporosis, rheumatoid arthritis, psoriasis, and Crohn's disease. Although the existence of a correlation between chronic inflammation, bone loss and increase of burner was already evident, it was not yet established whether the molecule was only a marker or actively participated in the process that resulted in a decrease in bone mass. According to Fukada, the molecule tested as a burner receptor antagonist is still in experimental use. Now we need to study the effect of quemerin on human osteoclasts to find out if we achieve the same effect. Source: Journal of Bone and Mineral Research.