A 46‐year‐old woman, with no personal or family history of m | Figure 1
A 46‐year‐old woman, with no personal or family history of melanoma, consulted for a naevus review. A 6‐mm brownish pigmented lesion was found in the abdomen, showing regular morphology and colour. Dermoscopic examination revealed a typical globular pattern with numerous white roundish structures distributed all over the lesion. The dermoscopic finding of white globules seems to correlate with nests of balloon cells. This finding should not be confused with milia‐like cysts. Balloon cells are melanocytes with extensive, pale‐staining and vacuolated cytoplasms, which often have a defect in melanosome formation. Reflectance confocal microscopy (RCM) showed larger cells with a central, roundish and large hyporefractive nucleus and a moderately refractive surrounding part, arranged in dense nests (blue arrows). The presence of typical globular pattern, the normal architecture and the absence of atypical cells on the RCM helps to identify this naevus. HE, haematoxylin and eosin.