### Disease Control Achieved Using Atezolizumab + Bevacizumab in a Patient With Sarcomatoid Hepatocellular Carcinoma (SHCC), a Rare Variant Excluded From the IMbrave150 Trial

Sarcomatoid hepatocellular carcinoma (SHCC) is a rare variant of liver cancer that lacks treatment options. The IMbrave trial demonstrated the efficacy of atezolizumab and bevacizumab (A + B) in patients with unresectable hepatocellular carcinoma but excluded patients with sarcomatoid variants. Herein, we describe a case of disease control achieved using the IMbrave regimen in a patient with sarcomatoid hepatocellular carcinoma.

[Read the full case here:](https://journals.sagepub.com/doi/full/10.1177/23247096221129470)

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### Extrahepatic Metastasis of Hepatocellular Carcinoma (HCC)

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### Cases of Hepatocellular Carcinoma

[Patient with #Hepatocellular-carcinoma presenting with progressive SOB.](https://app.figure1.com/case-detail/7918f8e1-5271-4e65-b5ce-416cb1e9a900)

[Axial T2-weighted MRI show a fibrolamellar hepatocellular carcinoma in the mid liver.](https://app.figure1.com/case-detail/81f6c7e0-8543-4207-9343-8c79b088f28d)

[Portal vein thrombosis in the setting of hepatocellular carcinoma; newly diagnosed HCV](https://app.figure1.com/case-detail/8551dc93-cdeb-4cd4-b007-a8529bd0a8b6)

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### Trending Cases

[A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis.](https://app.figure1.com/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a)

[A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back.](https://app.figure1.com/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5)

[A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days.](https://app.figure1.com/case-detail/48f41642-b9db-4089-b120-a94ee52328de)

[Patient in late teens presenting after a collapse, no previous cardiac history.](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)

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