#Thalassemias splenomegaly due to a beta thalassemia in a 1 | Figure 1

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Thalassemias splenomegaly due to a beta thalassemia in a 11 year old male

Case Description

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Case Summary

Woman with thalassemia major, blood transfusions every month, hemochromatosis. Diagnosis of diabetes (type 2?) for about 1 year. In metformin therapy. She exhibits glycemic diary that shows optimal values, but glycated hemoglobin is 7.5% (sampling performed about a week after transfusion). Considering that in thalassemia with frequent transfusions the glycated hemoglobin should be inappropriately low, how to explain this strong discrepancy?

Case Summary

A 25-year-old male, presented with fever for 2 weeks which is intermittent in nature, non productive cough for 1 week, and shortness of breath for the last 5 days. He has been a known case of thalassemia for 5 years. According to his mother's statement, he has been transfused with 85 bags of blood since. After clinical examination (we found features of consolidation and basal crep at the right lower zone), we have ordered a CXR. Eventually we diagnosed the case as CAP with thalassemia. But the interesting thing is that the chest X-ray finding of that thalassemic patient is once in a blue moon. Here in the chest X-ray, you can see the enlarged transverse process of the vertebra because of extensive extramedullary hematopoiesis. It is not enlarged lymph node.

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