Axial T1-weighted images of the brain in a patient with hype | Figure 1
CincyKidsRad
Cincinnati Children's Radiology
Axial T1-weighted images of the brain in a patient with hypermagnesemia and manganese toxicity show symmetric T1 hyperintense signal in the dentate nucleus (arrows, image 1), dorsal brainstem (arrow, image 2), cerebral peduncles (arrows, image 3), and globus pallidus (arrows, image 4). Manganese toxicity can cause symptoms similar to Parkinson's disease; the most common cause of negative toxicity is due to occupational exposure. However, genetic defects can cause an inborn error of manganese metabolism. #NeuroWednesday
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