Which of the following is NOT a contraindication for the yel | Figure 1

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Centers for Disease Control and Prevention


Which of the following is NOT a contraindication for the yellow fever vaccine?

A. People with a thymus disorder associated with abnormal immune cell function
B. People with HIV infection with CD4 T lymphocyte values <200/mm3 or <15% of total lymphocytes for children aged <6 years
C. History of hypersensitivity to the vaccine
D. Simultaneous administration of another vaccine.
E. Infants younger than 6 months old

CDC 2018 Yellow Book- Yellow Fever


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Researchers at Fiocruz Pernambuco have developed a new vaccine against yellow fever. Based on virus RNA, it was tested in mice and the results achieved 100% protection, even the index reached by the conventional vaccine currently offered by the Unified Health System (SUS).
Among the advantages of this new immunization is the possibility of being offered to the attenuated virus vaccine groups (children, pregnant women, elderly people, immunosuppressed persons and people with allergies to egg proteins), as well as large-scale production capacity.
The increased coverage of the DNA vaccine may be of more benefit to the population at the time of the disease outbreak, as is now the case in Brazil, where 1,170 suspected cases have been reported in six states, with deaths reported in three of them. Another advantage is that the new vaccine is safer.
According to Rafael Dhalia and Ernesto Marques (developers of the vaccine), the safety lies in the fact that the immunization is done without the presence of the live virus, even if weakened, which makes null the chance of adverse reactions and cause death by the fact of DNA is considered an inert molecule in our body. Before reaching the market, the vaccine created at Fiocruz Pernambuco needs to be tested on humans to ensure its safety and effectiveness.

NEW CDC Travel Health Notice: #YellowFever in Nigeria
There is a Yellow Fever (YF) outbreak in Nigeria. Travelers must be vaccinated against YF at least 10 days before travel. Some travelers may need a booster before they go. All travelers need to take steps to prevent mosquito bites.

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