Callosal dysgenesis | Figure 1

CincyKidsRad

Cincinnati Children's Radiology

Callosal dysgenesis

Sagittal T2-weighted with fat saturation (image 1), sagittal T1-weighted (image 2) MRI, and sagittal CT (image 4) reveal a central lipoma with absence/dysgenesis of the corpus callosum. Callosal dysgenesis, which can be complete or partial, is twice as common in males and has been associated with maternal alcohol consumption. It can also occur as part of syndromes and with other brain abnormalities. Approximately 10% of patients with callosal dysgenesis have lipomas.


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