JIMHICR

A Rare Case of Metastatic Hepatocellular Carcinoma to the Hard Palate

Extrahepatic metastasis of hepatocellular carcinoma (HCC) to the head and neck is unusual, especially the oral cavity/maxillofacial region. Metastatic HCC to the hard palate, however, is particularly rare. The most common site of HCC metastasis is the lung, followed by lymph nodes, bone, and adrenal gland. Importantly, oral cavity metastatic HCC may be misdiagnosed as a primary malignancy, such as a salivary gland carcinoma. In this article, we describe a young woman with metastatic HCC to the hard palate that was initially diagnosed as an acinic cell carcinoma.

Read the full case here:

More about this case

ResolvedVerified literatureRare

Why you should join Figure 1

• Share your knowledge with our global community of healthcare professionals
• Get help from experts in your field
• Learn from our library of real-world cases and quizzes

Similar cases

Bone metastasis in finger. Patient with lung carcinoma (large cell)](https://app.figure1.com/case-detail/3be5415e-c3f0-433e-9528-9af86c848b0b)


Asymptomatic small oral pigmented lesion of the hard palate discovered during routine oral examination. Differential diagnosis? Treatment?](https://app.figure1.com/case-detail/581300cc-5246-43e4-a120-f86b26e93f72)


This is an outrageous resection. Hard palate with attached septal cartilage. The arrow points to where the cancer is. Squamous cell carcinoma of the hard palate.](https://app.figure1.com/case-detail/85bc5ee1-b625-4070-a176-93501c79533e)


Metastatic #Squamous-cell-carcinoma](https://app.figure1.com/case-detail/8f62d3a5-74e0-4b70-b7e7-b8ba4208a988)

Trending now

A 52-year-old man presented with a 20-minute history of chest pain radiating to the left shoulder and neck, associated with dyspnea and diaphoresis. He had a history of hypertension, long-term smoking, and a sedentary lifestyle. On physical examination, bibasilar crackles were noted on lung auscultation. An electrocardiogram (ECG) was performed in the primary care setting, and the patient was promptly referred to the emergency department.](https://app.figure1.com/case-detail/ae0fe999-6875-4474-94f0-ad823dbb9b3a)


A 28-year-old woman presented with a 3-day history of intense pruritus over the lower back. She reported no recent travel or exposure to new environments. She cares for a small kennel with approximately eight dogs rescued from the streets. Physical examination revealed multiple small vesicles, some clustered and others scattered, predominantly involving the lumbar region and the left gluteal area.](https://app.figure1.com/case-detail/c271070f-2bc7-4052-9895-635277e1a7d5)


A 4-month-old male infant presented with skin lesions localized to the chin for the past 3 days. Physical examination revealed multiple small pustules with surrounding inflammatory signs on the chin, along with a few scattered papules on the chest.](https://app.figure1.com/case-detail/48f41642-b9db-4089-b120-a94ee52328de)


patient in late teens presenting after a collapse, no chest pain, no previous cardiac history, no history of sudden death in family, are there any features in this ekg that would warrant further work-up or is this just a pediatric ekg?](https://app.figure1.com/case-detail/2af390e1-ace8-40ed-ba1c-98fb2d72f4c5)