smallpox vaccine, vaccination shields, and inoculation lance | Figure 1

lilly230

Nurse Practitioner

smallpox vaccine, vaccination shields, and inoculation lancets. From the Dittrick Medical Museum.

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Which of the following is NOT a contraindication for the yellow fever vaccine? A. People with a thymus disorder associated with abnormal immune cell function B. People with HIV infection with CD4 T lymphocyte values <200/mm3 or <15% of total lymphocytes for children aged <6 years C. History of hypersensitivity to the vaccine D. Simultaneous administration of another vaccine. E. Infants younger than 6 months old

NEW! Visit Elsevier’s COVID-19 Healthcare Hub for the most current COVID-19 vaccine information. This Vaccine Toolkit provides the latest evidence-based information about vaccines approved for use to prevent COVID-19 infections. View vaccine drug monograph information as well as patient education resources. This page will continue to be updated as additional vaccines receive approval and new information becomes available.

A @DrsWithoutBorders frontline worker being vaccinated in Bikoro, Equateur Province, Democratic Republic of Congo (DRC). On May 8, 2018, an Ebola outbreak was declared in the north-west of DRC. As of June 5, 2018, there were 37 confirmed cases of Ebola and 27 deaths. @DrsWithoutBorders teams are currently in the areas of Mbandaka and Bikoro, where we have put two Ebola Treatment Centers in place. On May 28, 2018, @DrsWithoutBorders started vaccinating Ebola front-line workers in Bikoro. The Ebola vaccine rVSVDG-ZEBOV-GP is being used as part of an overall strategy to control the Ebola outbreak. This investigational vaccine has not yet been licensed and is being implemented through a study protocol. Participation is voluntary and vaccination is free. The vaccination will be administered using a “ring” approach, which involves identifying newly diagnosed and laboratory-confirmed Ebola patients and locating people they have come in contact with. Ebola health workers in the affected area will also be offered the possibility of vaccination, as they are most at risk of exposure to the virus and of developing the disease.

Cochrane Review; 52 studies with over 80,000 people, assessing the safety and effectiveness of influenza vaccines. About 70% reported insufficient detail. The results here come from 25 studies comparing inactivated vaccines with placebo or doing nothing. Injected influenza vaccines probably have a small protective effect against influenza and influenza like illness (ILI). 71 people would need to be vaccinated to avoid one influenza case, and 29 would need to be vaccinated to avoid one case of ILI. Vaccination may have little or no effect on the number of hospitalizations or working days lost. Vaccination slightly increases the risk of fever, but rates of nausea and vomiting are uncertain.

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