Skin Lesion in AAV | Figure 1

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Skin Lesion in AAV

A patient with recently diagnosed limited ANCA vasculitis presented with a worsening necrotic skin ulcer. She had been on methotrexate for sino-nasal disease but this lesion - which started "like a pimple" has been expanding over the past 2 months. Biopsy was significant for a neutrophillic dermatosis and consistent with a diagnosis of pyoderma gangrenosum. Her therapy was escalated to rituximab and she improved steadily over the coming months.

Diagnosis added by author

Pyoderma gangrenosum complicated ANCA vasculitis

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