this is cell block of pleural fluid from a 48-year-old woman | Figure 1

this is cell block of pleural fluid from a 48-year-old woman presenting with a 2-month cough and progressive dyspnea. seen are nests and clusters of atypical cells exhibiting enlarged, pleomorphic nuclei, inconspicuous nucleoli and scant to moderate, basophilic cytoplasm. some tumor cells form glands and acini filled with mucin.
DIAGNOSIS: pleural fluid positive for tumor cells (ADENOCARCINOMA)

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this is are H&E slides of a cell block from the pleural fluid of a 61/F presenting with masses in the mediastinum and right lung.
microscopic examination shows medium to large, cohesive, epithelioid cells with vesicular nuclei, prominent nucleoli and eosinophilic cytoplasm. also seen are frequent mitotic figures.
DIAGNOSIS: LYMPHOEPITHELIOMA-LIKE THYMIC CARCINOMA
*** this is classified as a type of poorly-differentiated squamous cell carcinoma***
*** currently performing CKAE and CD3 for further evaluation ***

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pleural fluid known lung cx.](https://app.figure1.com/case-detail/8999c96e-df26-4327-9282-9bb9ee36ee51)

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